Pathogenesis of experimental Pseudomonas keratitis in the guinea pig: bacteriologic, clinical, and microscopic observations.

Some observations on the feeding of the guinea pig

Comparison therapeutic effects of Ciprofloxacin, Silver nanoparticles and their combination in the treatment of Pseudomonas keratitis in rabbit: An experimental study

Pseudomonas aeruginosa is one of the most common causes of keratitis. The current study was done to evaluate the therapeutic effects of antibacterial combinations with Silver nanoparticles (Ag-NPs) and Ciprofloxacin in experimental Pseudomonas keratitis. Sixty four New Zealand rabbits were prepared. All rabbits were randomly categorized into eight groups (each group containing eight rabbits): C...

Studying the Mechanical Behavior of Tissue in the Generation of Pressure Sores using Simulation and a Guinea Pig Experimental Model

Introduction:  Pressure  sores  refer  to  lesions  that  are  produced  while  a  constant  pressure  causes  necrotic  tissue to grow. The need for a better comprehension of the process has led researchers to artificial generation  of  pressure  sores.  Modeling  the  mechanical  behavior  of tissue  will  provide  a better understanding  of this  process as well as a more suitable selection ...

Karyotype of Hairless Guinea pig

Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and G banding techniques. The chromosomes diploid number was 2n= 64 and polymorphism of three type chro...

Experimental Pseudomonas keratitis in the rabbit: bacteriologic, clinical, and microscopic observations.

Uniformly severe corneal infections were produced in rabbits by intracorneal injection of a few viable Pseudomonas aeruginosa. The bacteria multiplied rapidly, and within 24 hr, about 10 million organisms were present. The numbers remained stable thereafter. Polymorphonuclear leukocytes (PMNs) began to infiltrate peripheral stroma 24 hr after inoculation. By 32 hr, ring-shaped dense accumulatio...